Selected Recent Publications:

• Fujimoto KL, Clause KC, Liu LJ, Tinney JP, Verma S, Wagner W, Keller BB, Tobita K. Engineered fetal cardiac graft preserves its cardiomyocyte proliferation within post-infarcted myocardium and sustains cardiac function. Tissue Eng Part A. 2011 (in press).

• Tobita K, Liu X, Lo CW. Imaging modalities to assess structural birth defects in mutant mouse models. Birth Defects Res C Embryo Today. 2010 Sep;90(3):176-84.


• Okada M, Payne TR, Oshima H, Momoi N, Tobita K, Huard J. Differential efficacy of gels derived from small intestinal submucosa as an injectable biomaterial for myocardial infarct repair. Biomaterials. 2010 Oct;31(30):7678-83.


• Wainwright JM, Czajka CA, Paterl UB, Freytes DO, Tobita K, Gilbert TW, Badylak SF. Preparation of cardiac extracellular matrix from an intact porcine heart. Tissue Engineering Part C, 2009 (in press).


• Clause KC, Tinney JP, Liu JL, Gharaibeh B, Huard J, Kirk J, Shroff SG, Fujimoto LK, Wagner WR, Ralphe JC, Keller BB, Tobita K. A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle derived stem cells. Tissue Engineering Part C, 16(3):375-85.


• Fujimoto KL, Miki T, Liu LJ, Hashizume R, Strom SC, Wagner WR, Keller BB, Tobita K. Naïve rat amnion-derived cell transplantation improved left ventricular function and reduced myocardial scar of post-infarcted heart. Cell Transplantation, 2009; 18(4): 477-486


• Clause KC, Tinney JP, Liu JL, Keller BB, Tobita K. p38MAP-kinase regulates cardiomyocyte proliferation and contractile properties of engineered early embryonic cardiac tissue. Tissue Engineering, Part A. 2009, 15(6): 1373-1380.


• Momoi N, Tinney JP, Liu LJ, Elshershari H, Hoffmann PJ, Ralphe JC, Keller BB, Tobita K. Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth. Am J Physiol Heart Circ Physiol, 2008 May;294(5):H2248-56.


• Fujimoto KL, Tobita K, Merryman DW, Guan J, Momoi N, Stolz DB, Sacks MS, Keller BB, Wagner WR. Biodegradable cardiac patch induces contractile smooth muscle and prevents cardiac remodeling in sub-acute myocardial infarction. JACC 2007; 49: 2292-300


• Tobita K, Liu JL, Janczewski AM, Tinney JP, Nonemaker JM, Augustine S, Stolz DB, Shroff SG, Keller BB. Engineered early embryonic cardiac tissue (EEECT) retains proliferative and contractile properties of developing embryonic myocardium. Am J Physiol 2006: 291: H1829-1837.

CONTACT INFORMATION

Dr. Kimimasa Tobita, M.D.
Phone: 412-692-8190
Email: Kimimasa.Tobita@chp.edu