Dr. Sanjeev Shroff is Professor and Gerald E. McGinnis Chair in the Department of Bioengineering, as well as Professor of Medicine, at the University of Pittsburgh. Prior to joining the faculty, he received his Ph.D. in Bioengineering from the University of Pennsylvania in 1981 and completed his Postdoctoral Fellowship within the Cardiovascular-Pulmonary Division of the University of Pennsylvania Department of Medicine in 1982. Currently, in addition to his appointments at the University, Dr. Shroff is a participant in cardiovascular research at Allegheny General Hospital and the Allegheny-Singer Research Institute as well as Senior Investigator at the Magee-Womens Research Institute.
Recently, Dr. Shroff and his research collaborators have been featured in several publications for their efforts. His wide reaching research team includes basic and clinical scientists from Pittsburgh, PA (Magee-Womens Research Institute, Cardiovascular Institute, McGowan Institute for Regenerative Medicine, Allegheny General Hospital), Chicago, IL (University of Chicago Medical Center, Illinois Institute of Technology), and Pullman, WA (Washington State University).
Currently, Dr. Shroff is focusing his research efforts on two main areas of interest. An evaluation of the relationships between left ventricular mechano-energetic function and underlying cellular processes, with a special emphasis on contractile and regulatory proteins, is the focus of the first research area. Whole heart, isolated muscle, and single cell experiments are performed using various animal models, including transgenic mice. The second area focuses on the role of pulsatile arterial load (vascular stiffness in particular) in cardiovascular function. One of the hypotheses being investigated is that aberrant vascular stiffness changes are involved in the genesis of certain cardiovascular pathologies (e.g., preeclampsia, isolated systolic hypertension in elderly). Novel noninvasive measurement techniques are used to conduct longitudinal human studies, which are complimented by in-vivo and in-vitro vascular and cardiac studies with animal models. In addition, Dr. Shroff and colleagues have developed and continue to develop novel, simulation-based material (i.e., mathematical models of biological systems and associated "virtual experiments") for education and engineering design.
CONTACT INFORMATION
Dr. Sanjeev ShroffPhone: (412) 624-2095
Email: sshroff@pitt.edu