• Stella JA, D'Amore A, Wagner WR, Sacks MS.  On the biomechanical function of scaffolds for engineering load-bearing soft tissues.  Acta Biomaterialia.  2010 Jul;6(7):2365-81.  Epub 2010 Jan 7.
• D'Amore A, Stella JA, Wagner WR, Sacks MS.  Characterization of the complete fiber network topology of planar fibrous tissues and scaffolds.  Biomaterials.  2010 Jul;31(20):5345-54.  Epub 2010 Apr 15.
• Mirnajafi A, Zubiate B, Sacks MS.  Effects of cyclic flexural fatigue on porcine bioprosthetic heart valve heterograft biomaterials.  Journal of Biomedical Materials Research Part A.  2010 Jul;94(1):205-13.
• Parekh A, Cigan AD, Wognum S, Heise RL, Chancellor MB, Sacks MS.  Ex vivo deformations of the urinary bladder wall during whole bladder filling: contributions of extracellular matrix and smooth muscle.  Journal of Biomechanics.  2010 Jun 18;43(9):1708-16.  Epub 2010 Apr 15.
• Stella JA, Wagner WR, Sacks MS.  Scale-dependent fiber kinematics of elastomeric electrospun scaffolds for soft tissue engineering.  Journal of Biomedical Materials Research Part A.  2010 Jun 1;93(3):1032-42.
• Hashizume R, Fujimoto KL, Hong Y, Amoroso NJ, Tobita K, Miki T, Keller BB, Sacks MS, Wagner WR.  Morphological and mechanical characteristics of the reconstructed rat abdominal wall following use of a wet electrospun biodegradable polyurethane elastomer scaffold.  Biomaterials.  2010 Apr;31(12):3253-65.  Epub 2010 Feb 6.
• Gottlieb D, Kunal T, Emani S, Aikawa E, Brown DW, Powell AJ, Nedder A, Engelmayr GC Jr, Melero-Martin JM, Sacks MS, Mayer JE Jr.  In vivo monitoring of function of autologous engineered pulmonary valve.  Journal of Thoracic and Cardiovascular Surgery.  2010 Mar;139(3):723-31.
• Ramaswamy S, Gottlieb D, Engelmayr GC Jr, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE Jr, Sacks MS.  The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells.  Biomaterials.  2010 Feb;31(6):1114-25.  Epub 2009 Nov 26.
• Sales VL, Mettler BA, Engelmayr GC Jr, Aikawa E, Bischoff J, Martin DP, Exarhopoulos A, Moses MA, Schoen FJ, Sacks MS, Mayer JE Jr.  Endothelial progenitor cells as a sole source for ex vivo seeding of tissue-engineered heart valves.  Tissue Engineering Part A.  2010 Jan;16(1):257-67.
• Heise RL, Ivanova J, Parekh A, Sacks MS.  Generating elastin-rich small intestinal submucosa-based smooth muscle constructs utilizing exogenous growth factors and cyclic mechanical stimulation.  Tissue Engineering Part A.  2009 Dec;15(12):3951-60.
• Padala M, Hutchison RA, Croft LR, Jimenez JH, Gorman RC, Gorman JH 3rd, Sacks MS, Yoganathan AP.  Saddle shape of the mitral annulus reduces systolic strains on the P2 segment of the posterior mitral leaflet.  Annals of Thoracic Surgery.  2009 Nov;88(5):1499-504.
• Wognum S, Schmidt DE, Sacks MS.  On the mechanical role of de novo synthesized elastin in the urinary bladder wall.  Journal of Biomechanical Engineering.  2009 Oct;131(10):101018.
• Eckert CE, Zubiate B, Vergnat M, Gorman JH 3rd, Gorman RC, Sacks MS.  In vivo dynamic deformation of the mitral valve annulus.  Annals of Biomedical Engineering.  2009 Sep;37(9):1757-71.  Epub 2009 Jul 8.
• Parekh A, Long RA, Chancellor MB, Sacks MS.  Assessing the effects of transforming growth factor-beta1 on bladder smooth muscle cell phenotype. II. Modulation of collagen organization.  Journal of Urology.  2009 Sep;182(3):1216-21.  Epub 2009 Jul 21.
• Parekh A, Long RA, Iannone EC, Chancellor MB, Sacks MS.  Assessing the effects of transforming growth factor-beta1 on bladder smooth muscle cell phenotype. I. Modulation of in vitro contractility.  Journal of Urology.  2009 Sep;182(3):1210-5.  Epub 2009 Jul 21.
• Sacks MS, David Merryman W, Schmidt DE.  On the biomechanics of heart valve function.  Journal of Biomechanics.  2009 Aug 25;42(12):1804-24.  Epub 2009 Jun 21. Review.
• Wognum S, Lagoa CE, Nagatomi J, Sacks MS, Vodovotz Y.  An exploratory pathways analysis of temporal changes induced by spinal cord injury in the rat bladder wall: insights on remodeling and inflammation.  PLoS One.  2009 Jun 9;4(6):e5852.
• Williams C, Liao J, Joyce EM, Wang B, Leach JB, Sacks MS, Wong JY.  Altered structural and mechanical properties in decellularized rabbit carotid arteries.  Acta Biomaterialia.  2009 May;5(4):993-1005.  Epub 2008 Dec 11.
• Joyce EM, Moore JJ, Sacks MS.  Biomechanics of the fetal membrane prior to mechanical failure: review and implications.  European Journal of Obstetrics, Gynecology, and Reproductive Biology.  2009 May;144 Suppl 1:S121-7.  Epub 2009 Mar 19.  Review.
• Joyce EM, Liao J, Schoen FJ, Mayer JE Jr, Sacks MS.  Functional collagen fiber architecture of the pulmonary heart valve cusp.  Annals of Thoracic Surgery.  2009 Apr;87(4):1240-9.
• Merryman WD, Bieniek PD, Guilak F, Sacks MS.  Viscoelastic properties of the aortic valve interstitial cell.  Journal of Biomechanical Engineering.  2009 Apr;131(4):041005.
• Nguyen TD, Liang R, Woo SL, Burton SD, Wu C, Almarza A, Sacks MS, Abramowitch S.  Effects of cell seeding and cyclic stretch on the fiber remodeling in an extracellular matrix-derived bioscaffold.  Tissue Engineering Part A.  2009 Apr;15(4):957-63.
• Wang CC, Nagatomi J, Toosi KK, Yoshimura N, Hsieh JH, Chancellor MB, Sacks MS.  Diabetes-induced alternations in biomechanical properties of urinary bladder wall in rats.  Urology.  2009 Apr;73(4):911-5.  Epub 2009 Jan 24.
• Sacks MS, Schoen FJ, Mayer JE.  Bioengineering Challenges for Heart Valve Tissue Engineering.  Annual Review of Biomedical Engineering.  2009;11:289-313. Review.
• Parekh A, Sandulache VC, Singh T, Cetin S, Sacks MS, Dohar JE, Hebda PA.  Prostaglandin E2 differentially regulates contraction and structural reorganization of anchored collagen gels by human adult and fetal dermal fibroblasts.  Wound Repair and Regeneration.  2009 Jan-Feb;17(1):88-98.
• Gilbert TW, Wognum S, Joyce EM, Freytes DO, Sacks MS, Badylak SF.  Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix.  Biomaterials.  2008 Dec;29(36):4775-82. Epub 2008 Sep 17.
• Nguyen TD, Liang R, Woo SL, Burton SD, Wu C, Almarza A, Sacks MS, Abramowitch S. Effects of Cell Seeding and Cyclic Stretch on the Fiber Remodeling in an Extracellular Matrix-Derived Bioscaffold.  Tissue Engineering Part A.  2009 Apr;15(4):957-63.  Epub 2008 Sep 10.
• Toosi KK, Nagatomi J, Chancellor MB, Sacks MS.  The effects of long-term spinal cord injury on mechanical properties of the rat urinary bladder.  Annals of Biomedical Engineering.  2008 Sep;36(9):1470-80. Epub 2008 Jul 12.
• Vande Geest JP, Schmidt DE, Sacks MS, Vorp DA.  The effects of anisotropy on the stress analyses of patient-specific abdominal aortic aneurysms.  Annals of Biomedical Engineering.  2008 Jun;36(6):921-32. Epub 2008 Apr 9.
• Stella JA, Liao J, Hong Y, David Merryman W, Wagner WR, Sacks MS.  Tissue-to-cellular level deformation coupling in cell micro-integrated elastomeric scaffolds.  Biomaterials.  2008 Aug;29(22):3228-36. Epub 2008 May 12.
• Engelmayr GC Jr, Sacks MS.  Prediction of extracellular matrix stiffness in engineered heart valve tissues based on nonwoven scaffolds.  Biomechanics and Modeling in Mechanobiology.  2008 Aug;7(4):309-21. Epub 2007 Aug 23.
• Gray MA, Wang CC, Sacks MS, Yoshimura N, Chancellor MB, Nagatomi J.  Time-dependent alterations of select genes in streptozotocin-induced diabetic rat bladder.  Urology.  2008 Jun;71(6):1214-9. Epub 2008 Feb 15.

CONTACT INFORMATION

Dr. Michael Sacks
Email: msacks@pitt.edu
Phone: (412) 624-5302
Fax: (412) 624-5363
Office: Research: 450 Technology Drive, Suite 300
Teaching: Room 742 Benedum Hall
Lab: Engineered Tissue Mechanics Laboratory