Julie Phillippi, PhD

Selected recent publications:

  • Ker, E.D.F.,Chu, B., Phillippi, J.A., Gharaibeh, B., Huard, J., Weiss, L., and Campbell, P. Simultaneous differentiation of a single stem cell population towards osteoblast, tenocyte and myocyte fates in a spatially defined manner in registration to inkjet bioprinted growth factor patterns. Biomaterials. 2011. (accepted).
  • Payne, K.A., Meszaros, L.B., Phillippi, J.A. and Huard, J. Effect of PI3K, Erk1/2 and p38 MAPK Inhibition on Osteogenic Differentiation of Muscle-Derived Stem Cells. Tissue Engineering. 2010. 16 (12): 3647-55.
  • Phillippi, J.A., Eskay, M.A., Kubala, A.A., Pitt, B.R. and Gleason, T.G. Altered Oxidative Stress Response and Increased Type I Collagen Expression in Bicuspid Aortic Valve Patients. Annals of Thoracic Surgery. 2010. 90 (6): 1893-8.
  • Miller, E.D., Phillippi, J.A., Fisher, G.W., Campbell, P.G., Walker, L.M., and Weiss, L.E. Inkjet Printing of Growth Factor Concentration Gradients and Combinatorial Arrays Immobilized on Biologically-Relevant Substrates. Combinatorial Chemistry and Highthroughput Screening. 2009 12 (6): 604-18.
  • Phillippi, J.A., Klyachko, E.A., Kenny IV J.P., Eskay, M.A., Gorman. R.C. and Gleason, T.G. Basal and Oxidative Stress-Induced Expression of Metallothionein is Decreased in Ascending Aortic Aneurysms of Bicuspid Aortic Valve Patients. Circulation. 2009. 19 (18): 2498-2506.
  • Kubo S., Cooper G.M., Matsumoto T., Phillippi J.A., Corsi K.A., Usas A., Li G., Fu F.H. and Huard J. Blocking VEGF with sFlt1 improves the chondrogenic potential of mouse skeletal muscle-derived stem cells. Arthritis Rheum. 2009. 60 (1): 155-65.
  • Okada, M., Payne T. R., Zheng, B., Oshima, H., Momoi, N., Tobita, K., Keller, B. B., Phillippi, J.A., Peault, B. and Huard, J. Myocardial infarct repair using a novel human skeletal muscle-derived cell population with a hybrid myogenic and endothelial phenotype. JACC. 2008. 52 (23): 1869-80.
  • Nain, A., Phillippi, J.A., Sitti, M., MacKrell, J., Campbell, P. and Amon, C. Control of Cell Behavior by Aligned Micro/Nanofibrous Biomaterial Scaffolds Fabricated by Spinneret-based Tunable Engineered Parameters (STEP) Technique. Small. 2008. 4 (8): 1153-1159.
  • Phillippi JA, Miller E, Weiss L, Huard J, Waggoner A, Campbell P. Microenvironments engineered by inkjet bioprinting spatially direct adult stem cells toward muscle- and bone-like subpopulations. Stem Cells. 2008 Jan;26(1):127-34.
  • Chakraborty SK, Fitzpatrick JA, Phillippi JA, Andreko S, Waggoner AS, Bruchez MP, Ballou B. Cholera toxin B conjugated quantum dots for live cell labeling. Nano Lett. 2007 Sep;7(9):2618-26.
  • Corsi KA, Pollett JB, Phillippi JA, Usas A, Li G, Huard J. Osteogenic potential of postnatal skeletal muscle-derived stem cells is influenced by donor sex. J Bone Miner Res. 2007 Oct;22(10):1592-602.

  • Weiss KR, Cooper GM, Jadlowiec JA, McGough RL 3rd, Huard J. VEGF and BMP expression in mouse osteosarcoma cells. Clin Orthop Relat Res. 2006 Sep;450:111-7.

  • Koch H, Jadlowiec JA, Campbell PG. Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells. Stem Cells Dev. 2005 Dec;14(6):621-31.

  • Koch H, Jadlowiec JA, Whalen JD, Robbins P, Lattermann C, Fu FH, Merk HR, Hollinger JO. [Osteoblastic differentiation of human adult mesenchymal stem cells after through gene transfer of BMP-2 in the absence of dexamethasone]Z Orthop Ihre Grenzgeb. 2005 Nov-Dec;143(6):684-90. German.

  • Koch H, Jadlowiec JA, Whalen JD, Lattermann C, Robbins P, Fu FH, Merk H, Hollinger JO. [Refined adenoviral transduction for controlled gene transfer into human adult mesenchymal stem cells] Z Orthop Ihre Grenzgeb. 2005 Nov-Dec;143(6):677-83. German.

  • Jadlowiec JA, Zhang X, Li J, Campbell PG, Sfeir C. Extracellular matrix-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of bone morphogenetic protein. J Biol Chem. 2006 Mar 3;281(9):5341-7.

  • Jadlowiec J, Dongell D, Smith J, Conover C, Campbell P. Pregnancy-associated plasma protein-a is involved in matrix mineralization of human adult mesenchymal stem cells and angiogenesis in the chick chorioallontoic membrane. Endocrinology. 2005 Sep;146(9):3765-72.

  • Payne, K.A., Meszaros, L.B., Phillippi, J.A. and Huard, J. Effect of PI3K, Erk1/2 and p38 MAPK Inhibition on Osteogenic Differentiation of Muscle-Derived Stem Cells. Tissue Engineering. 2010. 16 (12): 3647-55.

  • Phillippi, J.A., Eskay, M.A., Kubala, A.A., Pitt, B.R. and Gleason, T.G. Altered Oxidative Stress Response and Increased Type I Collagen Expression in Bicuspid Aortic Valve Patients. Annals of Thoracic Surgery. 2010. 90 (6): 1893-8.

  • Ker, E.D.F.,Chu, B., Phillippi, J.A., Gharaibeh, B., Huard, J., Weiss, L., and Campbell, P. Simultaneous differentiation of a single stem cell population towards osteoblast, tenocyte and myocyte fates in a spatially defined manner in registration to inkjet bioprinted growth factor patterns. Biomaterials. 2011 (in press).

CONTACT INFORMATION

Julie Phillippi, PhD
Phone: (412) 624-6704
Email: phillippija@upmc.edu