Selected recent publications:

• Jagannathan J, Okonkwo DO, Yeoh HK, Dumont AS, Saulle D, Haizlip J, Barth JT, Jane JA Sr, Jane JA Jr.  Long-term outcomes and prognostic factors in pediatric patients with severe traumatic brain injury and elevated intracranial pressure.  Journal of Neurosurgery Pediatrics.  2008 Oct;2(4):240-9.
• Rangel-Castilla L, Gasco J, Nauta HJ, Okonkwo DO, Robertson CS.  Cerebral pressure autoregulation in traumatic brain injury.  Neurosurgical Focus.  2008 Oct;25(4):E7.  Review.
• Jones KE, Puccio AM, Harshman KJ, Falcione B, Benedict N, Jankowitz BT, Stippler M, Fischer M, Sauber-Schatz EK, Fabio A, Darby JM, Okonkwo DO.  Levetiracetam versus phenytoin for seizure prophylaxis in severe traumatic brain injury.  Neurosurgical Focus.  2008 Oct;25(4):E3.
• Tomycz ND, Chew BG, Chang YF, Darby JM, Gunn SR, Nicholas DH, Ochoa JB, Peitzman AB, Schwartz E, Pape HC, Spiro RM, Okonkwo DO.  MRI is unnecessary to clear the cervical spine in obtunded/comatose trauma patients: the four-year experience of a level I trauma center.  Journal of Trauma.  2008 May;64(5):1258-63.
• Reece TB, Tribble CG, Okonkwo DO, Davis JD, Maxey TS, Gazoni LM, Linden J, Kron IL, Kern JA.  Early adenosine receptor activation ameliorates spinal cord reperfusion injury.  Journal of Cardiovascular Medicine (Hagerstown).  2008 Apr;9(4):363-7.
• Sherman JH, Pouratian N, Okonkwo DO, Jane JA Jr, Laws ER.  Reconstruction of the sellar dura in transsphenoidal surgery using an expanded polytetrafluoroethylene dural substitute.  Surgical Neurology.  2008 Jan;69(1):73-6; discussion 76.
• Jagannathan J, Okonkwo DO, Prevedello DM, Kanter AS, Laws ER Jr.  Arachnoid diverticula associated with anterior cranial base tumors: technical case report.  Neurosurgery.  2007 Jul;61(1):E172-3; discussion E173.
• Jagannathan J, Okonkwo DO, Dumont AS, Ahmed H, Bahari A, Prevedello DM, Jane JA Sr, Jane JA Jr.  Outcome following decompressive craniectomy in children with severe traumatic brain injury: a 10-year single-center experience with long-term follow up.  Journal of Neurosurgery.  2007 Apr;106(4 Suppl):268-75.
• Sherman JH, Le BH, Okonkwo DO, Jane JA.  Supratentorial dural-based hemangioblastoma not associated with von Hippel Lindau complex.  Acta Neurochir (Wien).  2007;149(9):969-72; discussion 972.  Epub 2007 Jun 11.
• Reece TB, Kron IL, Okonkwo DO, Laurent JJ, Tache-Leon C, Maxey TS, Ellman PI, Linden J, Tribble CG, Kern JA.  Functional and cytoarchitectural spinal cord protection by ATL-146e after ischemia/reperfusion is mediated by adenosine receptor agonism.  Journal of Vascular Surgery.  2006 Aug;44(2):392-7.
• Reece TB, Okonkwo DO, Ellman PI, Maxey TS, Tache-Leon C, Warren PS, Laurent JJ, Linden J, Kron IL, Tribble CG, Kern JA.  Comparison of systemic and retrograde delivery of adenosine A2A agonist for attenuation of spinal cord injury after thoracic aortic cross-clamping.  Annals of Thoracic Surgery.  2006 Mar;81(3):902-9.
• Okonkwo DO, Reece TB, Laurent JJ, Hawkins AS, Ellman PI, Linden J, Kron IL, Tribble CG, Stone JR, Kern JA.  A comparison of adenosine A2A agonism and methylprednisolone in attenuating neuronal damage and improving functional outcome after experimental traumatic spinal cord injury in rabbits.  Journal of Neurosurgery Spine.  2006 Jan;4(1):64-70.
• De Tommasi C, Vance ML, Okonkwo DO, Diallo A, Laws ER Jr.  Surgical management of adrenocorticotropic hormone-secreting macroadenomas: outcome and challenges in patients with Cushing's disease or Nelson's syndrome.  Journal of Neurosurgery.  2005 Nov;103(5):825-30.
• Kanter AS, Diallo AO, Jane JA Jr, Sheehan JP, Asthagiri AR, Oskouian RJ, Okonkwo DO, Sansur CA, Vance ML, Rogol AD, Laws ER Jr.  Single-center experience with pediatric Cushing's disease.  Journal of Neurosurgery.  2005 Nov;103(5 Suppl):413-20.
• Reece TB, Okonkwo DO, Ellman PI, Warren PS, Smith RL, Hawkins AS, Linden J, Kron IL, Tribble CG, Kern JA.  The evolution of ischemic spinal cord injury in function, cytoarchitecture, and inflammation and the effects of adenosine A2A receptor activation.  Journal of Thoracic Cardiovascular Surgery.  2004 Dec;128(6):925-32.
• Stone JR, Okonkwo DO, Dialo AO, Rubin DG, Mutlu LK, Povlishock JT, Helm GA.  Impaired axonal transport and altered axolemmal permeability occur in distinct populations of damaged axons following traumatic brain injury.  Experimental Neurology.  2004 Nov;190(1):59-69.
• Reece TB, Davis JD, Okonkwo DO, Maxey TS, Ellman PI, Li X, Linden J, Tribble CG, Kron IL, Kern JA.  Adenosine A2A analogue reduces long-term neurologic injury after blunt spinal trauma.  Journal of Surgical Research.  2004 Sep;121(1):130-4.

CONTACT INFORMATION

Dr. David O. Okonkwo
Phone: (412) 647-3685
Email: okonkwodo@upmc.edu