Selected recent publications:

• Nejak-Bowen KN, Thompson MD, Singh S, Bowen WC Jr, Dar MJ, Khillan J, Dai C, Monga SP.  Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin.  Hepatology.  2010 May;51(5):1603-13.
• Prince JM, Vodovotz Y, Baun MJ, Monga SP, Billiar TR, Gerlach JC.  The nitric oxide donor S-nitrosoglutathione reduces apoptotic primary liver cell loss in a three-dimensional perfusion bioreactor culture model developed for liver support.  Tissue Engineering Part A.  2010 Mar;16(3):861-6.
• Behari J, Yeh TH, Krauland L, Otruba W, Cieply B, Hauth B, Apte U, Wu T, Evans R, Monga SP.  Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis.  Americal Journal of Pathology.  2010 Feb;176(2):744-53.  Epub 2009 Dec 17.
• Nejak-Bowen KN, Zeng G, Tan X, Cieply B, Monga SP.  Beta-catenin regulates vitamin C biosynthesis and cell survival in murine liver.  Journal of Biological Chemistry.  2009 Oct 9;284(41):28115-27.  Epub 2009 Aug 18.
• Monga SP.  Role of Wnt/beta-catenin signaling in liver metabolism and cancer.  International Journal of Biochemistry and Cell Biology.  2009 Sep 9.  [Epub ahead of print]
• Apte U, Singh S, Zeng G, Cieply B, Virji MA, Wu T, Monga SP.  Beta-catenin activation promotes liver regeneration after acetaminophen-induced injury.  American Journal of Pathology.  2009 Sep;175(3):1056-65.  Epub 2009 Aug 13.
• Apte U, Gkretsi V, Bowen WC, Mars WM, Luo JH, Donthamsetty S, Orr A, Monga SP, Wu C, Michalopoulos GK.  Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase.  Hepatology.  2009 Sep;50(3):844-51.
• Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, Liu Y.  Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria.  Journal of the American Society of Nephrology.  2009 Sep;20(9):1997-2008.  Epub 2009 Jul 23.
• He W, Dai C, Li Y, Zeng G, Monga SP, Liu Y.  Wnt/beta-catenin signaling promotes renal interstitial fibrosis.  Journal of the American Society of Nephrology.  2009 Apr;20(4):765-76.  Epub 2009 Mar 18.
• Cieply B, Zeng G, Proverbs-Singh T, Geller DA, Monga SP.  Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.  Hepatology.  2009 Mar;49(3):821-31.
• Tan X, Yuan Y, Zeng G, Apte U, Thompson MD, Cieply B, Stolz DB, Michalopoulos GK, Kaestner KH, Monga SP.  Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development.  Hepatology.  2008 May;47(5):1667-79.
• Nejak-Bowen K, Monga SP.  Wnt/beta-catenin signaling in hepatic organogenesis.  Organogenesis.  2008 Apr;4(2):92-9.
• Apte U, Thompson MD, Cui S, Liu B, Cieply B, Monga SP.  Wnt/beta-catenin signaling mediates oval cell response in rodents.  Hepatology.  2008 Jan;47(1):288-95.

CONTACT INFORMATION

Satdarshan P. Singh Monga, M.D.
Phone: (412) 648-9966
Email: mongass@upmc.edu