Satdarshan (Paul) Singh Monga, M.D.

Dr. Monga holds an Endowed Research Chair in Experimental Pathology and serves as the Director-Division of Experimental Pathology. Dr. Monga is Professor of Pathology (Division of Experimental Pathology), Professor of Medicine (Division of Gastroenterology, Hepatology & Nutrition), University of Pittsburgh, and he also serves as the Director: Cellular Approaches to Tissue Engineering and Regeneration (CATER) Program. Dr. Monga holds a M.D. in medicine and surgery from Dayanand Medical College and Hospital, Ludhiana, and Punjab University, Chandigarh, India.

Prior to arriving at the university, Dr. Monga completed a multidisciplinary internship at the Dayanand Medical College and Hospital and several fellowships. He participated in a Postdoctoral Fellowship in Gastroenterology/Molecular Biology at Temple University Fels Cancer Institute, Philadelphia, and the Veterans Association Medical Center in Washington D.C., Virginia, and a Research Fellowship in Gastroenterology/Molecular Biology at the Georgetown University Hospital and Veterans Affairs Medical Center in Washington D.C., Virginia. Additionally, he held the position of medical officer in charge at the Dayanand Medical College and Hospital, Department of Social and Preventative Medicine, before arriving in coming to Pittsburgh as a Research Associate within the Department of Pathology of the University of Pittsburgh School of Medicine.

Dr. Monga is a member of several professional societies and has been the recipient of several prestigious awards. Currently he is a member of the American Association of Cancer Research (AACR), American Gastroenterology Association (AGA), American Society of Investigative Pathology (ASIP) and the Society of Developmental Biology (SDB). He has also been nominated for the Fellow of the Year Award by the American Association (1998) and the Senior Vice Chancellor Award (2002) at the university. Dr. Monga has been recognized recently with the Pathology Postdoctoral Research Training Award (1999) and for having the President Plenary Distinguished Abstract in Gastrointestinal Oncology at the 2002 Annual AGA Conference.

Dr. Monga has also been featured in several publications for his research efforts. His primary interests lie in:

  • Hepatic stem cell characterization, culture and transplantation including intra-uterine transplants, utilizing in vitro embryonic liver model and antisense and transgenic techniques
  • Wnt/b -catenin signaling pathway in liver utilizing liver regeneration model, primary hepatocyte cultures, embryonic liver development and transgenic models. Identifying novel targets of this pathway with emphasis on role in liver development and carcinogenesis
  • Study cross talk between prominent signal transduction pathways, especially Wnt, HGF and TGF pathways. Identifying novel targets and elucidating interactions during development, growth and carcinogenesis
  • Studying carcinogenesis and utilizing novel approaches to identify cancer progenitor cells in liver and gut. Applying antisense technology to study carcinogenesis and possible therapeutic role

Past research projects under his direction have included Wnt/Beta - catenin in liver development and Beta-Catenin and HGF in liver cancer. Currently, Dr. Monga is involved in research concerning the following:

  • Wnt/Beta - catenin in liver


Satdarshan P. Singh Monga, M.D.
Phone: (412) 648-9966