Selected recent publications:

• Wang D, Li Y, Wu C, and Liu Y.  2011.  PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression.  PLoS One.  6: e17048. 
• Dai C, Wen X, He W, and Liu Y.  2011.  Inhibition of pro-inflammatory RANTES expression by TGF-1 is mediated by glycogen synthase kinase-3-dependent -catenin signaling.  J. Biol. Chem.  286: 7052-7059.
• He W, Kang YS, Dai C, and Liu Y.  2011.  Blockade of Wnt/-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury.  J. Am. Soc. Nephrol.  22: 90-103.
• Liu Y.  2010.  New insights into epithelial-mesenchymal transition in kidney fibrosis.  J. Am. Soc. Nephrol.  21: 212-222.
• Hao S, Shen H, Hou Y, Mars WM, and Liu Y.  2010.  tPA is a potent mitogen for renal interstitial fibroblasts: role of 1 integrin/focal adhesion kinase signaling.  Am. J. Pathol.  177: 1164-1175. 
• Wen X, Li Y, and Liu Y.  2010.  Opposite action of peroxisome proliferator-activated receptor- in regulating renal inflammation: functional switch by its ligand.  J. Biol. Chem.  285: 29981-29988. 
• He W, Tan R, Dai C, Li Y, Wang D, Hao S, Kahn M, and Liu Y.  2010.  Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/-catenin signaling.  J. Biol. Chem.  285: 24665-
• Kang YS, Li Y, Dai C, Kiss LP, Wu C, and Liu Y.  2010.  Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria.  Kidney Int.  78: 363-373. 
• Dai C, Saleem MA, Holzman LB, Mathieson P, and Liu Y.  2010.  Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria.  Kidney Int.  77: 962-973. 
• Li J, Wilson A, Gao X, Kuruba R, Liu Y, Poloyac S, Pitt B, Xie W, and Li S.  2009.  Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginie.  J. Pharmacol. Exp. Ther.  331: 234-243.
• Tan X, He W, and Liu Y.  2009.  Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy.  Kidney Int.  76: 1248-1257.
• Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, and Liu Y.  2009.  Wnt/-catenin signaling promotes
• Li Y, Tan X, Dai C, Stolz DB, Wang D, and Liu Y.  2009.  Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.  J. Am. Soc. Nephrol.  20: 1907-1918.
• He W, Dai C, Li Y, Zeng G, Monga SP, and Liu Y.  2009.  Wnt/-catenin signaling promotes renal interstitial fibrosis.  J. Am. Soc. Nephrol.  20: 765-776.
• Tan R, He W, Lin X, Kiss LP, and Liu Y.  2008.  Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity and functional implication.  Am. J. Physiol. Renal Physiol.  294: F1076-F1083.

CONTACT INFORMATION

Dr. Youhua Liu
Phone: (412) 648-8253
Email: yhliu@pitt.edu