John A. Kellum, MD, FACP, FCCM

Dr. John Kellum is a Professor in the Departments of Critical Care Medicine (primary), Medicine, Bioengineering, and Clinical and Translational Science at the University of Pittsburgh. He is also the Director of the Center for Critical Care Nephrology and the Vice-Chair for Research, both appointments in the Department of Critical Care Medicine, and Associate Director for Acute Illness in the Institute for Personalized Medicine at Pitt. Dr. Kellum also serves as an Intensivist in the Cardiothoracic ICU at UPMC.

Dr. Kellum received his MD at the Medical College of Ohio at Toledo in 1988 and then completed his residency at the University of Rochester. Dr. Kellum completed a Fellowship in Critical Care Medicine at UPMC Presbyterian Hospital.

Dr. Kellumís research interests span various areas, including:

  • Mechanisms of organ failure in sepsis and strategies to reduce organ injury
  • Acute renal failure/acute kidney injury
  • Hemofiltration in the treatment of multiple organ dysfunction and systemic inflammatory response
  • Acid-base balance
  • Shock and resuscitation
  • Biomarkers
  • Bioengineering
  • Organ donor management

A recipient of a $2.7 million award from the National Institute of Diabetes and Digestive and Kidney Diseases, Dr. Kellum will examine the natural history of acute kidney injury (AKI) arising in patients with sepsis using patients from the ProCESS trial. Through another NIH $2.3 million award, his work will determine circulating levels of inflammatory molecules during recovery from a severe infection as well as its relationship with subsequent development of a heart attack or stroke. He and his team will also determine whether, for an infection, different treatment strategies implemented during the hospital course alter levels of inflammatory molecules after hospital discharge. This information is important to design future treatment plans toward improved health outcomes.

Dr. Kellum is a member of the editorial boards and subject/theme editor for Nephrology, Dialysis and Transplantation, Shock and Critical Care. He is associate editor for Blood Purification. He also is a journal referee for many publications, including but not limited to, The New England Journal of Medicine, JAMA, Critical Care Medicine, the American Journal of Physiology, Intensive Care Medicine, the Journal of the American Society of Nephrology and The Lancet.

View a list of Dr. Kellumís publications here.


Dr. John Kellum
phone: 412-647-7810