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Song XJ, Simplaceanu V, Ho NT, Ho C. Effector-Induced Structural Fluctuation Regulates the Ligand Affinity of an Allosteric Protein: Binding of Inositol Hexaphosphate Has Distinct Dynamic Consequences for the T and R States of Hemoglobin. Biochemistry. 2008 Apr 1.[E-pub ahead of print]
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Foley LM, Hitchens TK, Melick JA, Bayir H, Ho C, Kochanek PM. Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice. J Neurotrauma. 2008 Apr;25(4):299-310.
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Song XJ, Yuan Y, Simplaceanu V, Sahu SC, Ho NT, Ho C. A Comparative NMR Study of the Polypeptide Backbone Dynamics of Hemoglobin in the Deoxy and Carbonmonoxy Forms, Biochemistry 46, 2007 6795-6803.
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Li D, Manjula BN, Ho NT, Simplaceanu V, Ho C, Acharya AS. Acharya AS. Molecular Aspects of the High Oxygen Affinity of Non-Hypertensive Hexa Pegylated Hemoglobin, [(SP-PEG5K)6-Hb], Artificial Cells, Blood Substitutes, and Biotechnology 35, 2007 19-29. (2007).
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Williams JB, Ye Q, Hitchens TK, Kaufman CL, Ho C. MRI Detection of Macrophages Labeled Using Micrometer-Sized Iron Oxide Particles, Journal of Magnetic Resonance Imaging 25, 2007 1210-1218.
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Shen TJ, Rogers H, Yu X, Lin F, Noguchi CT, Ho C. Modification of globin gene expression by RNA targeting strategies. Exp Hematol. 2007 Aug;35(8):1209-18.
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Vasseur-Godbillon C, Sahu SC, Domingues E, Fablet C, Giovannelli JL, Tam TC, Ho NT, Ho C, Marden MC, Baudin-Creuza V. Recombinant hemoglobin betaG83C-F41Y.
FEBS J. 2006 Jan;273(1):230-41. -
Kneipp J, Balakrishnan G, Chen R, Shen TJ, Sahu SC, Ho NT, Giovannelli JL, Simplaceanu V, Ho C, Spiro TG. Dynamics of allostery in hemoglobin: roles of the penultimate tyrosine H bonds. J Mol Biol. 2006 Feb 17;356(2):335-53. Epub 2005 Nov 22.
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Wu YL, Ye Q, Foley LM, Hitchens TK, Sato K, Williams JB, Ho C. In situ labeling of immune cells with iron oxide particles: an approach to detect organ rejection by cellular MRI. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1852-7.
CONTACT INFORMATION
Dr. Chien Ho
Phone: (412) 268-3395
Email: chienho@cmu.edu