Selected recent publications:

• Gorelik M, Torok KS, Kietz DA, Hirsch R. Hypocomplementemia associated with macrophage activation syndrome in systemic juvenile idiopathic arthritis and adult onset still's disease: 3 cases. J Rheumatol [Internet]. 2011;38(2):396-7.
• Wilson DC, Marinov AD, Blair HC, Bushnell DS, Thompson SD, Chaly Y, Hirsch R. Follistatin-like protein 1 is a mesenchyme-derived inflammatory protein and may represent a biomarker for systemic-onset juvenile rheumatoid arthritis. Arthritis Rheum [Internet]. 2010;62(8):2510-6.
• Rosenkranz ME, Wilson DC, Marinov AD, Decewicz A, Grof-Tisza P, Kirchner D, Giles B, Reynolds PR, Liebman MN, Kolli VSK, Thompson SD, Hirsch R. Synovial fluid proteins differentiate between the subtypes of juvenile idiopathic arthritis. Arthritis Rheum [Internet]. 2010;62(6):1813-23.
• Patel AM, Brown AG, Galambos C, Hirsch R. Pediatric pigmented villonodular synovitis mimicking a septic hip. Journal of Clinical Rheumatology [Internet]. 2010;16(2):71-3.
• Clutter SD, Wilson DC, Marinov AD, Hirsch R. Follistatin-like protein 1 promotes arthritis by up-regulating IFN-γ. Journal of Immunology [Internet]. 2009;182(1):234-9.
• Hirsch R. Is long-term etanercept therapy safe and effective in patients with juvenile RA? Nature Clinical Practice Rheumatology [Internet]. 2008;4(12):628-9.
• Traister RS, Hirsch R. Gene therapy for arthritis. Modern Rheumatology [Internet]. 2008;18(1):2-14.
• Spalding SJ, Kent CK, Boudreau R, Enama J, Lunich J, Huber D, Denes L, Hirsch R. Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: A potential tool for quantifying arthritis. Arthritis Research and Therapy [Internet]. 2008;10(1)
• Huber AM, Dugan EM, Lachenbruch PA, Feldman BM, Perez MD, Zemel LS, Lindsley CB, Rennebohm RM, Wallace CA, Passo MH, Reed AM, Bowyer SL, Ballinger SH, Miller FW, Rider LG, Colbert R, DeInocencio J, Griffin T, Hashkes P, Hirsch R, Kredich D, Laxer R, Levinson J, Lovell D, Ruperto N, Silverman E, Sundel R, Vogelgesang S. The cutaneous assessment tool: Development and reliability in juvenile idiopathic inflammatory myopathy. Rheumatology [Internet]. 2007;46(10):1606-11.
• Reinhardt A, Hirsch R. Gene therapy for rheumatoid arthritis. Future Rheumatology [Internet]. 2007;2(4):403-13.
• Spalding SJ, Meza MP, Ranganathan S, Hirsch R. Staphylococcus aureus panniculitis complicating juvenile dermatomyositis. Pediatrics [Internet]. 2007;119(2):e528-30.
• Miyamae T, Marinov AD, Sowders D, Wilson DC, Devlin J, Boudreau R, Robbins P, Hirsch R. Follistatin-like protein-1 is a novel proinflammatory molecule. Journal of Immunology [Internet]. 2006;177(7):4758-62.
• Traister RS, Fabre S, Wang Z, Xiao X, Hirsch R. Inflammatory cytokine regulation of transgene expression in human fibroblast-like synoviocytes infected with adeno-associated virus. Arthritis Rheum [Internet]. 2006;54(7):2119-26.
• Irie J, Wu Y, Wicker LS, Rainbow D, Nalesnik MA, Hirsch R, Peterson LB, Leung PSC, Cheng C, Mackay IR, Gershwin ME, Ridgway WM. NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis. J Exp Med [Internet]. 2006;203(5):1209-19. 
• Miyamae T, Malehorn DE, Lemster B, Mori M, Imagawa T, Yokota S, Bigbee WL, Welsh M, Klarskov K, Nishomoto N, Vallejo AN, Hirsch R. Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy. Arthritis research & therapy. [Internet]. 2005;7(4):R746-755.

CONTACT INFORMATION

Dr. Raphael Hirsch, M.D.
Phone: (412) 692-5970
Email: Raphael.Hirsch@chp.edu