Joseph C. Glorioso III, Ph.D.
Selected recent publications:

  • Chattopadhyay, M., Goss, J., Wolfe, D., Goins, W. F., Huang, S., Glorioso, J. C., Mata, M., Fink, D. J. Protective effect of herpes simplex virus-mediated neurotrophin gene transfer in cisplatin neuropathy. Brain. 127 (Pt4): 929-39, 2004.

  • Niranian, A., Wolfe, D., Fellows, W., Goins, W. F., Glorioso, J. C., Kondziolka, D., Lunsford, L.D. Gene   transfer to glial tumors using herpes simplex virus. Methods Mol. Biol.   246: 323-37, 2004.

  • Goins, W. F.,Wolfe, D., Krisky, D. M., Bai, Q., Burton, E. A., Fink, D. J., Glorioso, J. C. Delivery using herpes           simplex virus: an overview. Methods Mol. Biol. 246: 257-99, 2004.

  • Goss, J. R., Natsume, A., Wolfe, D., Mata, M., Glorioso, J. C., Fink, D. J. Delivery of herpes simplex virus-based vectors to the nervous system.  Methods Mol. Biol. 246: 309-22, 2004.

  • Wolfe, D., Wechuck, J. B., Krisky, D. M., Goff, J. P., Goins, W. F., Ozuer, A., Epperly, M.E., Greenberger, J. S., Fink, D. J., Glorioso, J. C.  Delivery of herpes simplex virus-based vectors to stem cells.  Methods Mol. Biol. 246: 339-52, 2004.

  • Mata, M., Glorioso, J.C., Fink, D. J.  Gene therapy: novel treatments for polyneuropathy and chronic pain.  Curr. Neurol Neurosci. Rep.  4 (1): 1-2, 2004.

  • Bennett, N.E., Kim, J.H., Katsumi, S., Yoshimura, N., Wolfe, D.P., Goins, W.F., Nelson, J.B. de Groat, W.C., Glorioso, J.C., Chancellor, M.B. Improvement of Erectile Dysfunction after Neurotrophic Factor Gene Therapy in Diabetic Rats.

  • Sasaki, K., Chancellor, M.B., Goins, W.F., Phelan, M.W., Glorioso, J.C., de Groat, W.C., and Yoshimura, N. Gene Therapy Using Replication Defective Herpes Simplex Virus Vectors Expressing Nerve Growth Factor in a Rat Model of Diabetic Cystopathy. Diabetes. 53:  2723-2730. 2004.

  • Jiang, C., Wechuck, J.B., Goins,.W.F., Krisky, D. M., Wolfe, D., Ataai, M.M., and Glorioso, J.C.  Immobilized Cobalt Affinity Chromatography Provides a Novel, Efficient Method for Herpes Simplex Virus Type 1 Gene Vector Purification. J. Virology. 78 (17): 8994-9006, 2004.

  • Glorioso, J.C. and Fink, D.J.  Herpes Vector-Mediated Gene Transfer in Treatment of Diseases of the Nervous System. Annu. Rev. Microbiol. (58) : 253-71, 2004

  • Nakano, K., Todo, T., Zhao, G., Yamaguchi, K., Kuroki,S., Cohen, J.B., Glorioso, J.C., and Tanaka, M.  Enhanced efficacy of conditionally replicating herpes simplex virus (G207) combined with 5-fluorouracil surgical resection in peritoneal cancer dissemination models. 2004 (in press)

  • Puskovic, V., Wolfe, D., Goss, J., Huang, S., Mata, M., Glorioso, J.C., and Fink, D.J. Prolonged Biologically Active Transgene Expression Driven by HSV LAP2 in Brain in Vivo. Molecular Therapy. 10:67-75, 2004.

  • Wolfe, D., Niranjan, A., Trichel, A., Wiley, C., Ozuer, A., Kanal, E., Kondziolka, D., Krisky, D., Goss, J., DeLuca, N., Murphey-Corb, M. and Glorioso, J.C. Safety and Biodistribution Studies of an HSV Multigene Vector Following Intracranial Delivery to Non-Human Primates. Gene Therapy (11): 1675-1684, 2004.

  • Liu, J., Wolfe, D., Hao, S., Huang, S., Glorioso, J.C., Mata, M. and Fink, D.J. Peripherally Delivered Glutamic Acid Decarboxylase Gene Therapy for Spinal Cord Injury Pain. Molecular Therapy Vol 10, 57-66.  2004.

  • Nakano, K., Asano, R., Tsumoto, K., Kwom, H., Goins, W.F., Kumagai, I., Cohen, J.B., and Glorioso, J.C.  Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule. 2004 (in press)



CONTACT INFORMATION


Dr. Joseph C. Glorioso III
Phone: (412) 6924-2519
Email: glorioso@pitt.edu