Joseph C. Glorioso III, Ph.D.

Selected recent publications:

  • Baek H, Uchida H, Jun K, Kim J, Kuroki M, Cohen JB, Glorioso JC, Kwon H. Bispecific adapter-mediated retargeting of a receptor-restricted HSV-1 vector to CEA-bearing tumor cells. Mol Ther. 2010 Oct 5.
  • Frampton AR Jr, Uchida H, von Einem J, Goins WF, Grandi P, Cohen JB, Osterrieder N, Glorioso JC. Equine herpesvirus type 1 (EHV-1) utilizes microtubules, dynein, and ROCK1 to productively infect cells. Vet Microbiol. Feb 24;141(1-2):12-21 (EPub 209 Aug 8). 2010
  • Wolfe D, Craft AM, Cohen JB, Glorioso JC. An hsv vector system for expression and selection of complex cellular cdna libraries. J. Virol. Jul; 84 (14): 7360-8. (Epub 2010) May 12. 2010
  • Glorioso JC, Fink DJ. Herpes vector-mediated gene transfer in the treatment of chronic pain.  Mol Ther. Jan; 17(1):13-8.  Epub Oct 7, 2009
  • Goss JR, Gold MS, Glorioso JC.  HSV vector-mediated modification of primary nociceptor afferents: an approach to inhibit chronic pain.  Gene Ther, Apr; 16(4):493-501, 2009.
  • Glorioso JC, Fink DJ.  Gene therapy for pain: introduction to the special issue.  Gene Ther, Apr 16(4):453-4, 2009.
  • Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC. Design and application of oncolytic HSV vectors for glioblastoma therapy.  Expert Rev Neurother, Apr; 9(4):505-17, 2009.
  • Goins WF, Goss JR, Chancellor BM, deGroat WC, Glorioso JC, Yoshimura N.  Herpes simplex virus vector-mediated gene delivery for the treatment of lower urinary tract pain. Gene Ther. Apr; 16(4):558-69. Epub  Feb 26, 2009
  • Grant K, Krisky D, Ataai MM, Glorioso JC.  Engineering cell lines for production of replication defective HSV-1 gene therapy vectors.  Biotechnol Bioeng, Mar 1; 102(4):1087-97, 2009
  • Miyazato M, Sugaya K, Goins WF, Goss JR, Chancellor MB, deGroat WC, Glorioso JC, Yoshimura N.  Herpes simplex virus vector-medicated gene delivery of glutamic acid decarboxylase reduces detrusor overactivity in spinal cord injurie rats. Gene Ther May; 16(5):660-8 Rpub, Feb 19, 2009
  • Yokoyama H, Sasaki K, Franks ME, Goins WF, Goss JR, deGroat W, Glorioso JC, Chancellor MB,  Yoshimura N. Gene therapy for bladder overactivity and nociception with herpes simple virus vectors expressing   preproenkephalin.  Hum Gene Ther. Jan 20(1):63-71, 2009
  • Uchida H, Shah WA, Ozuer A, Frampton AR, Goins WF, Grandi P, Cohen JB, Glorioso JC. Generation of HVEM-restricted HSV-1 mutant viruses: Resistance of HVEM-expressing cells and identification of mutations that rescue nectin-1 recognition. J Virol. Apr; 83(7):2951-61. Epub. Jan 7, 2009
  • Srinivasan R, Wolfe D, Goss JR, Watkins S, deGroat W, Sculptoreanu A, Glorioso JC.  PKCε contributes to basal and sensitizing responses of TRPV1 to capsaicin in dorsal root ganglion neurons. Eur J Neurosci Oct; 28(7); 1241-54. 2008
  • Srinivasan R, Fink DJ, Glorioso JC.  HSV vectors for gene therapy of chronic pain.  Curr Opin Mol Ther,  Oct;10(5):449-55. Review. 2008

CONTACT INFORMATION

Dr. Joseph C. Glorioso III
Phone: (412) 6924-2519
Email: glorioso@pitt.edu