Jörg C. Gerlach, M.D., Ph.D.
Selected recent publications:- Schmelzer E, Triolo F, Turner ME, Thompson RL, Zeilinger K, Reid LM, Gridelli B, Gerlach JC. Three-dimensional perfusion bioreactor culture supports differentiation of human fetal liver cells. Tissue Engineering Part A. 2010 Jun;16(6):2007-16.
- Lübberstedt M, Müller-Vieira U, Mayer M, Biemel KM, Knöspel F, Knobeloch D, Nüssler AK, Gerlach JC, Zeilinger K. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro. Journal of Pharmacological and Toxicological Methods. 2010 May 9. [Epub ahead of print]
- Gerlach JC, Brayfield C, Puhl G, Borneman R, Müller C, Schmelzer E, Zeilinger K. Lidocaine/Monoethylglycinexylidide Test, Galactose Elimination Test, and Sorbitol Elimination Test for Metabolic Assessment of Liver Cell Bioreactors. Artificial Organs. 2010 Apr 27. [Epub ahead of print]
- Prince JM, Vodovotz Y, Baun MJ, Monga SP, Billiar TR, Gerlach JC. The nitric oxide donor S-nitrosoglutathione reduces apoptotic primary liver cell loss in a three-dimensional perfusion bioreactor culture model developed for liver support. Tissue Engineering Part A. 2010 Mar;16(3):861-6.
- Gerlach JC, Lübberstedt M, Edsbagge J, Ring A, Hout M, Baun M, Rossberg I, Knöspel F, Peters G, Eckert K, Wulf-Goldenberg A, Björquist P, Stachelscheid H, Urbaniak T, Schatten G, Miki T, Schmelzer E, Zeilinger K. Interwoven Four-Compartment Capillary Membrane Technology for Three-Dimensional Perfusion with Decentralized Mass Exchange to Scale Up Embryonic Stem Cell Culture. Cells, Tissues, Organs. 2010 Feb 27. [Epub ahead of print]
- Gerlach JC, Hout M, Edsbagge J, Björquist P, Lübberstedt M, Miki T, Stachelscheid H, Schmelzer E, Schatten G, Zeilinger K. Dynamic 3D culture promotes spontaneous embryonic stem cell differentiation in vitro. Tissue Engineering. Part C, Methods. 2010 Feb;16(1):115-21.
- Jozefczuk J, Stachelscheid H, Chavez L, Herwig R, Lehrach H, Zeilinger K, Gerlach JC, Adjaye J. Molecular Characterization of Cultured Adult Human Liver Progenitor Cells. Tissue Engineering. Part C, Methods. 2010 Jan 11. [Epub ahead of print]
- Catapano G, Patzer JF 2nd, Gerlach JC. Transport advances in disposable bioreactors for liver tissue engineering. Advances in Biochemical Engineering/Biotechnology. 2010;115:117-43.
- Wohlers I, Stachelscheid H, Borstlap J, Zeilinger K, Gerlach JC. The Characterization Tool: A knowledge-based stem cell, differentiated cell, and tissue database with a web-based analysis front-end. Stem Cell Research. 2009 Sep-Nov;3(2-3):88-95. Epub 2009 May 18.
- Schmelzer E, Mutig K, Schrade P, Bachmann S, Gerlach JC, Zeilinger K. Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver support. Biotechnology and Bioengineering. 2009 Feb 10. [Epub ahead of print]
- Lin YC, Brayfield CA, Gerlach JC, Peter Rubin J, Marra KG. Peptide modification of polyethersulfone surfaces to improve adipose-derived stem cell adhesion. Acta Biomaterialia. 2008 Dec 24. [Epub ahead of print]
- Stachelscheid H, Urbaniak T, Ring A, Spengler B, Gerlach JC, Zeilinger K. Isolation and Characterization of Adult Human Liver Progenitors from Ischemic Liver Tissue Derived from Therapeutic Hepatectomies. Tissue Engineering. Part A. 2008 Dec 24. [Epub ahead of print]
- Dong J, Mandenius CF, Lübberstedt M, Urbaniak T, Nüssler AK, Knobeloch D, Gerlach JC, Zeilinger K. Evaluation and optimization of hepatocyte culture media factors by design of experiments (DoE) methodology. Cytotechnology. 2008 Jul;57(3):251-61. Epub 2008 Oct 7.
- Gerlach JC, Zeilinger K, Patzer Ii JF. Bioartificial liver systems: why, what, whither? Regenerative Medicine. 2008 Jul;3(4):575-95.
- Johnen C, Steffen I, Beichelt D, Bräutigam K, Witascheck T, Toman N, Moser V, Ottomann C, Hartmann B, Gerlach JC. Culture of subconfluent human fibroblasts and keratinocytes using biodegradable transfer membranes. Burns. 2008 Aug;34(5):655-63. Epub 2008 Jan 15.
- Brayfield CA, Marra KG, Leonard JP, Tracy Cui X, Gerlach JC. Excimer laser channel creation in polyethersulfone hollow fibers for compartmentalized in vitro neuronal cell culture scaffolds. Acta Biomaterialia. 2008 Mar;4(2):244-55. Epub 2007 Oct 24.
CONTACT INFORMATION
Dr. Jörg Gerlach
Phone: 412-383-7150
Email: jgerlach@pitt.edu