• Meng Xiang, Lianhua Yin, Yuehua Li, Guozhi Xiao, Yoram Vodovotz, Timothy R. Billiar, Mark A. Wilson, and Jie Fan.  Hemorrhagic Shock Activates Lung Endothelial NAD(P)H Oxidase Via Neutrophil NADPH Oxidase. Am. J. Respir. Cell  Mol. Biol. 2011 44:333-340.
• G Papia, Jie Fan, A Kapus, K Szaszi, J Marchall, P Tawadros, M Ailenberg, and Rotstein. Altered Inhibitory kappa-B alpha expression in LPS-stimulated alveolar macrophages following resuscitated hemorrhagic shock. Shock 2011 35(2):171-177.
• H Cao, S Yu, Z Yao, DL Galson, Y Jiang, X Zhang, Jie Fan, B Lu, Y Guan, M Luo, Y Lai, Y Zhu, N Kurihara, K Patrene, GD Roodman, G Xiao. Activating transcription factor 4 regulates osteoclast differentiation in mice. J Clin Invest. 2010 120(8):2755-66.
• Meng Xiang and Jie Fan. Pattern Recognition Receptor-Dependent Mechanisms of Acute Lung Injury. Molecular Medicine 2010 16(1-2):69-82.
• David J. Kaczorowski, Amin Afrazi, Melanie J. Scott, Joon H. Kwak, Roop Gill, Rebecca D. Edmonds, Yuejian Liu, Jie Fan, and Timothy R. Billiar. The Pattern Recognition Receptor Ligands Lipopolysaccharide and Polyinosine-Polycytidylic Acid Stimulate Factor B Synthesis by the Macrophage. J. Leukocyte Biol. 2010 88(4):609-18
• Jie Fan. Receptor Cross-Talk Mechanisms of Neutrophil Priming. Chapter in the book Granulocytes: Classification, Toxic Materials Produced and Pathology. Edited by: Frank Columbus. Nova Science Publishers, Inc. New York 2010.
• S Yu, R Franceschi, M Luo, Jie Fan, D Jiang, H Cao, Y Lai, J Zhang, K Patrene, K Hankenson, D Roodman, and G Xiao. Critical Role of Activating Transcription Factor 4 in the Anabolic Actions of Parathyroid Hormone in Bone. P Los One 2009 4(10):e7583
• Y Li, M Xiang, Y Yuan, G Xiao, J Zhang, Y Vodovotz, TR. Billiar, MA. Wilson, and Jie Fan. Hemorrhagic Shock Augments Lung Endothelial Cells Activation: Role of Temporal Alteration of TLR4 and TLR2. Am J Physiol. 2009 297:R1670-R1680.
• Yujian Liu, Youzhong Yuan, Yuehua Li, Jian Zhang, Guozhi Xiao, Yoram Vodovotz, Timothy R. Billiar, Mark A. Wilson, and Jie Fan. Interacting Neuro-endocrine, Innate, and Acquired Immune Pathways Regulate Neutrophil Mobilization from Bone Marrow following Hemorrhagic Shock. J. Immunol. 2009, 182:572-580
• Jie Fan, Y Li, RLevy, JJ. Fan, DJ. Hackam, Y Vodovotz, H Yang, KJ Tracey, TR Billiar, and MAWilson. Hemorrhagic Shock Induces NAD(P)H Oxidase Activation in Neutrophils: Role of HMGB1-TLR4 Signaling. J Immunol 2007, 178:6573-6580
• Jie Fan, Y Li, Y Vodovotz, TR Billiar, and MA Wilson. Neutrophil NAD(P)H Oxidase is Required for Hemorrhagic Shock-Enhanced TLR2 Upregulation in Alveolar Macrophages in Response to LPS. Shock 2007, 28(2):213-218
• Jie Fan, Yuehua Li, Yoram Vodovotz, Timothy R. Billiar and Mark A. Wilson. Hemorrhagic shock-activated neutrophils augment tlr4 signaling-induced tlr2 upregulation in alveolar macrophages:role in hemorrhage primed lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2006 290:738-746.
• Zhou X, Gao XP, Jie Fan, Liu Q, Anwar KN, Frey RS, Malik AB. Toll-like receptor 4 (TLR4) induces the expression of CD11b/CD18 integrin in neutrophils1. Am. J. Physiol. Lung Cell. Mol. Physiol. 2005 288(4):L655-62.
• Oreopoulos GD, Wu H, Szaszi K, Jie Fan, Marshall JC, Khadaroo RG, He R, Kapus A, Rotstein OD. Hypertonic preconditioning prevents hepatocellular injury following ischemia/reperfusion in mice: a role for interleukin 10. Hepatology. 2004 40(1):211-20.
• Jie Fan and AB Malik. Toll-like receptor 4 signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat. Med. 2003 9(3): 315.
• Jie Fan, RS Frey, and AB Malik. TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. J. Clin. Invest. 2003 112 :1234-1243.
• Jie Fan, RS Frey, A Rahman, and AB Malik. Role of neutrophil NADPH oxidase in the mechanism of TNF?-induced NF-?B activation and ICAM-1 expression in Endothelial cells. J. Biol. Chem. 2002 277(5): 3404-3411.

CONTACT INFORMATION

Dr. Jie Fan
Phone: (412) 688-6634
Email: jif7@pitt.edu