Dr. Anthony Demetris is currently a Professor of Pathology and Director, Division of Transplantation
Pathology at the Starzl Transplantation Institute. He joined the Institute in 1986 after attending
medical school and completing his residency at the University of Pittsburgh Medical Center, in the
Department Anatomic and Clinical Pathology. Dr. Demetris currently teaches graduate courses in Digestion
and Nutrition, Immunology and Human Disease, and Transplant and Immunology.
In addition to his to his academic positions, Dr. Demetris is actively involved clinical research. Since his appointment with the University, he has been featured in several publications for his works, including 400 research papers, 38 Invited Reviews, Editorials, Letters and 33 book chapters. His primary research interests lie in:
- Organ allograft pathology
- Progression of chronic liver disease
- Improving morbidity-free long-term solid organ allograft survival through induction of hematopoietic chimerism and tolerance and chronic allograft rejection
- Use of bioinformatics in transplant-related outcomes-based research and treatment of liver disease/fibrosis with the use of cytokines and growth factors.
Dr. Demetris currently holds medical privileges at the University of Pittsburgh Medical Center and has reviewed over 20,000 liver allograft biopsies. He has served as a Consultant for Wyeth-Ayerst Research, Roche Pharmaceuticals and Novartis Pharmaceuticals. He holds memberships with numerous organizations including the American Society of Clinical Pathologists, ransplantation Society, American Association of Pathologists, Federation of American Societies for Experimental Biology, and International Society for Heart and Lung Transplantation. He has also been awarded membership of Alpha Omega Alpha and a Resident Research Award from the Pittsburgh Academy of Medicine and recognized as a PEW Scholar Program Candidate from the University of Pittsburgh.
Currently, Dr. Demetris holds a patent for Method of Regulating Dendritic Cell Maturation and is involved in research projects concerning:
- Defined histopathology of allograft dysfunction syndromes after transplantation
- Co-discovered persistence of donor hematolymphoid cells after transplantation and concept of microchimerism
- Coordination of the Banff working group in development of an international consensus grading and staging system for acute and chronic liver allograft rejection
- IL-6 functions as a growth factor for biliary epithelial cells.
CONTACT INFORMATION
Anthony J. Demetris, MD
Phone: (412) 647-2067
Email: demetrisaj@upmc.edu