Stephen F. Badylak DVM, PhD, MD

Selected recent publications:

  • Freytes, D.O., Tullius, R., Badylak, S.F. The Effect of Storage upon Material Properties of Lyophilized Porcine Extracellular Matrix Derived from the Urinary Bladder.  JBMR:b – Applied Biomaterials, 2006.  78(2):327-33.

  • Gilbert, T.W., Stewart-Akers, A.M., Simmons-Byrd, A., Badylak, S.F.  Degradation and Remodeling of Small Intestinal Submucosa in Canine Achilles Tendon Repair. JBJS – Am. 2007 Mar; 89(3):621-30.

  • Valentin, J.E., Badylak, J.S., McCabe, G. P., Badylak, S.F. Extracellular Matrix bioscaffolds for Orthopaedic Applications:  A Comparative Histologic Study. JBJS.  2006. 88(12):2673-86.

  • Badylak, S.F.  Regenerative Medicine and Developmental Biology: The Role of the Extracellular Matrix.  New Anat, 2005. 287(1):36-41.

  • Gurewich, V., Pannell, R., Simmons-Byrd, A., Sarmientos, P., Liu, J., Badylak, S.F. Thrombolysis versus Bleeding from Hemostatic Sites by a Prourokinase Mutant Compared with Tissue Plasminogen Activator.  J Thrombosis & Haemostasis. 4:1559-1565. 

  • Gilbert, T.W., Sellaro, T.L., Badylak, S. F.  Decellularization of Tissues and Organs.  Biomaterials, 2006. 27(19):3675-83. 

  • Nieponice, A., Gilbert, T. W., Badylak, S. F.  Reinforcement of Esophageal Anastomoses with an Extracellular Matrix Scaffold in a Canine Model.  Annals of Thoracic Surgery. 2006. 82(6):2050-8.

  • Brennan, E. P., Reing, J., Chew, D., Myers-Irvin, J. M., Young, E. J., Badylak, S. F. Antibacterial Activity within Degradation Products of Biologic Scaffolds Composed of Extracellular Matrix.  Tissue Engineering, 2006. 12(10):2949-2955.

  • Freytes, D. O., Tullius, R. S., Valentin, J. E., Stewart-Akers, A. M., Badylak, S. F. Hydrated vs Lyophilized forms of Porcine Extracellular Matrix Derived from the Urinary Bladder.  JBMR:a. (in press).  

  • Gilbert, T. W., Stewart-Akers, A. M., Badylak, S. F. A Quantitative Method for Evaluating the Degradation of Biologic Scaffold Materials. Biomaterials, 2007. 28:147-150.

  • Brune T, Borel A, Gilbert TW, Franceschi JP, Badylak SF, Sommer P: In vitro comparison of human fibroblasts from intact and ruptured ACL for use in tissue engineering.  Euro Cell Mater J. 2007 Dec 17;14:78-91.

  • Ota, T., Gilbert, T. W., Badylak, S. F., Schwartzman, D., Zenati, M. A.  Electromechanical Characterization of a Tissue-Engineered Myocardial Patch Derived from Extracellular Matrix. J Thorac Cardiovasc Surg. 2007 Apr 133(4):979-985.

  • Borovetz, H.S., Badylak, S.F., Boston, J.R., Johnson, C., Kormos, R., Kameneva, M.V., Simaan, M., Snyder, T.A., Tsukui, H., Wagner, W.R., Woolley, J., Antaki, J., Diao, C., Vandenberghe, S., Keller, B., Morell, V., Wearden, P., Webber, S., Gardiner, J., Li, C.M., Paden, D., Paden, B., Snyder, S., Wu, J., Bearnson, G., Hawkins, J.A., Jacobs, G., Kirk, J., Khanwilkar, P., Kouretas, P.C., Long, J., Shaddy, R. E.  Towards the Development of a Pediatric Ventricular Assist Device.  Cell Transplantation, 2006. 15 [suppl I] (12):69-74.

  • Gilbert, T.W., Stewart-Akers, A.M., Sydeski, J., Nguyen, T.D, Badylak, S.F., Woo, S.L. Gene Expression by Fibroblasts Seeded on Small Intestinal Submucosa and Subjected to Cyclic Stretching. Tissue Engineering, 2007, 13(6):1313-23.

  • Freytes, D.O., Stoner, R., Badylak, S.F. Uniaxial and Biaxial Properties of Terminally Sterilized Porcine Urinary Bladder Matrix.  JBMR-B 2008 Feb; 84(2): 408-14.

  • Sellaro, T.L., Ravindra, A.K., Beer-Stoltz, D., Badylak, S.F. Maintenance of Hepatic Endothelial Cell Phenotype In Vitro Using Organ-Specific Extracellular Matrix Biologic Scaffolds. Tissue Engineering. 2007 Sep;13(9):2301-10

  • Badylak, S.F. The Extracellular Matrix as a Biologic Scaffold Material. Biomaterials, 2007. 28:3587-3593.

  • Marra, K.G.; DeFail, A.J.; Clavijo-Alvarez, J.A.; Badylak, S.F.; Taieb, A.; Schipper, B.; Bennett, J.; Rubin, J.P. FGF-2 Enhances Vascularization for Adipose Tissue Engineering. Plastic Recon. Surg 2008 Apr; 121(4):1153-64.

  • Freytes, D.O., Martin, J., Velankar, S.S., Lee, A.S., Badylak, S.F.  Preparation and Rheological Characterization of a Gel Form of the Porcine Urinary Bladder Matrix.Biomaterials, 2008 29:1630-1637.

  • Badylak, S.F. and Gilbert, T.W. Immune Response to Biologic Scaffold Materials. Seminars in Immunology, 2008 20:109-116.

CONTACT INFORMATION

Dr. Stephen Badylak
Phone: 412-235-5145
Email: badylaks@upmc.edu
Lab Website: www.mirm.pitt.edu/badylak/