Dr. Steffi Oesterreich is a Professor of Pharmacology and Chemical Biology at the University of Pittsburgh Cancer Institute. She is also the Director of Education at the Women's Cancer Research Center, a collaboration between the Magee Women's Research Institute and University of Pittsburgh Cancer Institute. In addition, Dr. Oesterreich is a Graduate Faculty Member of the Interdisciplinary Biomedical Graduate Program in Molecular Pharmacology and in Molecular Pathology at the University of Pittsburgh School of Medicine.
Dr. Oesterreich received her BS in Biochemistry at the Humboldt University, Berlin, Germany, in 1989. In 1992, she received her PhD in Molecular Medicine from the Humboldt University, Max-Delbrück Center for Molecular Medicine, Berlin, Germany. Post-graduation, she participated in a Fellowship in Breast Cancer at the University of Texas Health Science Center in San Antonio, Texas, and spent some time in Germany as an Alexander-von-Humboldt-Fellow.
A list of Dr. Oesterreich’s current research interests includes:
Endocrine treatment resistance in breast cancer
Genetic (e.g. SNPs) and epigenetic (e.g. DNA methylation, histone modifications) changes causatively associated with resistance
Invasive Lobular Cancer (ILC)
Transition from LCIS to ILC
Unique properties of ILC (compared to IDC)
Hormone response in ILC
Clinical relevance and mechanism of action of:
Crosstalk between steroid receptor and growth factor signaling
Hormone response in ovarian cancer
Dr. Oesterreich is the Chair of the Tumor Cell Biology Study Section as well as an International Grant Reviewer for The Breast Cancer Campaign (London, UK), The Dutch Cancer Society, Health Research Board Clinical Research Training Fellowship (Ireland), Science Foundation Ireland, and the Association for International Cancer Research (AICR).
Dr. Oesterreich is on the Editorial Boards for several journals, including Endocrinology, Endocrine-Related Cancer, and Hormones and Cancer. She is also a Reviewer for numerous journals, including but not limited to Oncogene, Nature Medicine, JCI, MCB, Cancer Research, Experimental Cell Research, FEBS Letters, Genomics, Journal Biological Chemistry, The Journal of Molecular Endocrinology, the Journal of Molecular Medicine, theJournal of the National Cancer Institute, and Molecular Carcinogenesis.
View a list of Dr. Oesterreich’s publications here.