Dr. Ora Weisz is a Professor in the Department of Medicine (Renal-Electrolyte Division) and in the Department of Cell Biology, University of Pittsburgh. She is also the Vice Chair for Faculty Development in the Department of Medicine and the Assistant Dean for Faculty Development in Pitt’s School of Medicine. She holds a BS (cum laude) in Molecular Biophysics and Biochemistry/History from Yale University in New Haven, Connecticut, and received her PhD in Biochemistry, Cellular and Molecular Biology in 1990 from the Johns Hopkins School of Medicine in Baltimore, Maryland. Upon completion of her post-doctoral training at Johns Hopkins, Dr. Weisz joined the University of Pittsburgh faculty in 1995 as an Assistant Professor within the School of Medicine.
Dr. Weisz’s research interest is in the regulation of apical membrane traffic in renal epithelial cells. The highly selective delivery and retrieval of newly synthesized proteins and lipids to the apical plasma membrane is necessary for maintaining the transport and barrier functions of epithelial tissues. She and her team are interested in unraveling the mechanisms by which proteins are selected for apical delivery, incorporated into vesicular carriers, and targeted to the appropriate membrane. Additionally, her laboratory has been unraveling the mechanisms by which proximal tubule cells alter endocytic uptake in response to changes in flow and the accompanying fluid shear stress. This project has potential implications for the treatment of genetic and other disorders that manifest with low molecular weight proteinuria.
Dr. Weisz is an active member of the American Society for Cell Biology and the American Physiological Society. She is an alumnus of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) program and was recently elected to the Johns Hopkins Society of Scholars. She is a member of the Academy of Master Educators, University of Pittsburgh School of Medicine, and has received the School of Medicine Distinguished Mentor Award and the University of Pittsburgh Postdoctoral Association Advocate Award. Dr. Weisz currently serves on the editorial board ofPhysiological Reviews, Traffic, American Journal of Physiology - Cell Physiology, and Frontiers in Membrane Traffic. She serves on the Board of Scientific Counselors for the NIH National Heart, Lung, and Blood Institute and was recently elected to Council of the American Society of Cell Biology.
View a list of Dr. Weisz’s publications here.