Dr. Ora Weisz is a Professor in the Department of Medicine (Renal-Electrolyte Division) and in the Department of Cell Biology, University of Pittsburgh. She is also the Vice Chair for Faculty Development in the Department of Medicine and the Assistant Dean for Faculty Development in Pitt’s School of Medicine. She holds a BS (cum laude) in Molecular Biophysics and Biochemistry/History from Yale University in New Haven, Connecticut, and received her PhD in Biochemistry, Cellular and Molecular Biology in 1990 from the Johns Hopkins School of Medicine in Baltimore, Maryland. Upon completion of her post-doctoral training at Johns Hopkins, Dr. Weisz joined the University of Pittsburgh faculty in 1995 as an Assistant Professor within the School of Medicine.
Dr. Weisz’s research interest focuses broadly on understanding how membrane traffic in proximal tubule cells responds to physiologic cues to maintain kidney function. Her team is unraveling the mechanisms by which newly synthesized proteins are sorted and delivered to the appropriate plasma membrane domains of differentiated kidney cells. Additionally, they have been generating new in vitro and ex vivo systems, including disease models, to determine how proximal tubule cells in the kidney alter their endocytic and ion transport capacity in response to changes in tubular flow and the accompanying fluid shear stress. These studies have direct implications for the understanding and treatment of genetic and other disorders that result in tubular proteinuria and eventually lead to kidney failure, including Lowe syndrome and sickle cell disease.
Dr. Weisz is an active member of the American Society for Cell Biology and the American Physiological Society. She is an alumnus of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) program and was recently elected to the Johns Hopkins Society of Scholars. She is a member of the Academy of Master Educators, University of Pittsburgh School of Medicine, and has received the School of Medicine Distinguished Mentor Award and the University of Pittsburgh Postdoctoral Association Advocate Award. Dr. Weisz currently serves on the editorial board of Physiological Reviews, Traffic, American Journal of Physiology- Cell Physiology, and Frontiers in Membrane Traffic. She serves on the Board of Scientific Counselors for the NIH National Heart, Lung, and Blood Institute and on the Council of the American Society of Cell Biology.
View a list of Dr. Weisz’s publications here.