Dr. Wagner’s research interests are generally in the area of cardiovascular engineering with projects that address medical device biocompatibility and design, tissue engineering, and targeted imaging. His research group is comprised of graduate students in Bioengineering and Chemical Engineering as well as post-doctoral fellows with backgrounds in surgery, polymer chemistry, or engineering. Dr. Wagner and his group enjoy working across the spectrum from in vitro to clinical studies. The McGowan Institute and the University of Pittsburgh Medical Center are uniquely positioned to allow such broad-based projects to flourish and complement one another. Researchers within Dr. Wagner’s group are afforded the opportunity to observe first-hand the clinical successes and failures of currently employed cardiovascular devices while concurrently working on projects that attempt to describe the current modes of failure, test solutions for the current device shortcomings, or develop technologies that may find application as future cardiovascular therapies. The front-line experience afforded by the clinical environment has proven invaluable in the learning experience of group members, not to mention the input such experience has on the creative environment.