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Limb Regeneration

Due to advances in defensive technology and medical care, soldiers are more likely to survive engagements in Afghanistan and Iraq. However the number of soldiers suffering amputations is more than twice what has been seen in previous wars (The Journal of Life Sciences, Sept 2007). The goal of this project is to attempt to regenerate the amputated toe of a mouse using extracellular matrix (ECM) by stimulating the body to regrow the lost digit. Toes are surgically amputated and various compounds are placed into or near the wound and the results are quantified by histological and immunohistochemical stains.


Updated 16-May-2011